KUVAN® (sapropterin dihydrochloride) Tablets for Oral Use and Powder for Oral Solution are approved to reduce blood Phe levels in people with a certain type of Phenylketonuria (PKU). KUVAN is to be used with a Phe-restricted diet.
Important Safety Information
It is not possible to know if KUVAN will work for you without a trial of the medicine. Your doctor will check your blood Phe levels when you start taking KUVAN to see if the medicine is working.
Starting KUVAN does not eliminate the need for ongoing dietary management. Any change to your diet may impact your blood Phe level. Follow your doctor's instructions carefully. Your doctor and dietitian will continue to monitor your diet and blood Phe levels throughout your treatment with KUVAN to make sure your blood Phe levels are not too high or too low. If you have a fever, or if you are sick, your Phe level may go up. Tell your doctor and dietitian as soon as possible so they can make any necessary changes to your treatment.
Children younger than 7 years old treated with KUVAN doses of 20 mg/kg per day are at an increased risk for low levels of blood Phe compared with children 7 years and older. Frequent blood monitoring is recommended in this population to ensure that blood Phe levels do not fall too low.
Tell your doctor if you have ever had liver or kidney problems, have poor nutrition or have a loss of appetite, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed.
KUVAN is a prescription medicine and should not be taken by people who are allergic to any of its ingredients. KUVAN and other medicines may interact with each other. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, herbal and dietary supplements.
If you forget to take your dose of KUVAN, take it as soon as you remember that day. Do not take 2 doses in a day. If you take too much KUVAN, call your doctor for advice.
The most common side effects reported when using KUVAN are headache, runny nose and nasal congestion, sore throat, diarrhea, vomiting, and cough. Additional adverse reactions reported in connection with worldwide marketing include sore throat, heartburn or pain in the esophagus, inflammation of the lining of the stomach, indigestion, stomach pain, and nausea. These are not all the possible side effects seen with KUVAN. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
KUVAN can cause serious side effects, including:
- Severe allergic reactions. Stop taking KUVAN and get medical help right away if you develop any of these symptoms of a severe allergic reaction:
- Wheezing or trouble breathing
- Lightheadedness or fainting
- Inflammation of the lining of the stomach (gastritis). Gastritis can happen with KUVAN and may be severe. Call your doctor right away if you have any:
- Severe upper stomach-area discomfort or pain
- Blood in your vomit or stool
- Nausea and vomiting
- Black, tarry stools
- Too much or constant activity (hyperactivity) can happen with KUVAN. Tell your doctor if you have any signs of hyperactivity, including fidgeting, moving around or talking too much.
For more information, call BioMarin Patient and Physician Support (BPPS) at 1-866-906-6100. Please read the full Patient Information by clicking here.
Air Force School of Aerospace Medicine (USAFSAM) is an internationally renowned center for aerospace medical learning, consultation, aerospace medical investigations and aircrew health assessments. Order your own custom USAFSAM ceramic mugs with a minimum order of 12 different mug types. Each mug is personalized with any name or callsign. Each person can choose different images on the back, or even the side of their mug. Reorders are quick and easy, expect about 6 weeks for production. Insights from this study are important for understanding malapposition as cheap proscar
a quantitative, rather than binary phenomenon (present or absent) and to define the threshold of ISA detachment that might benefit from optimization during stent implantation. Late catch-up phenomenon regarding stent thrombosis and TLR was significantly more pronounced with SES than that with BMS. This limitation should remain the target for improvements of DES technology. Intracoronary infusion of BMMNC is safe, but does not enhance cardiac function on MRI-derived parameters, nor does it improve clinical outcome. By allowing us to continue to send you these C. To learn about the benefits of membership visit Member Services section of our website. There you will learn about our lending Library, The CN Journal and our Coin Insurance Program. Become a member of our association. Past issues of the E-BULLETIN have been converted to Adobe Acrobat Portable Document Format (pdf) for your reading pleasure and are stored on our servers for you to download and enjoy. American Association of Hospital Dentists. Academy of Dentistry for the Handicapped. American Society for Geriatric Dentistry. Spontaneous rupture of common iliac vein. Case report a literature review. The 63th general scientific meeting of surgical association, Taiwan. Roan JN, Luo CY, Kan CD, Lin PY, Wen JS, Lai CH, Yang YJ. In situ reconstruction of septic aortic pseudoaneurysm due to microbial aortitis: Long-term Follow-up Taipei, The 63th general scientific meeting of surgical association, Taiwan. Lin PY, Yang YJ, Jan MY, Hsn TJ..
West Palm Beach, Florida, 1995. The New York Hospital Medical Center of Queens, The First Research Seminar. A New Radioactive Source for Intraoperative Brachytherapy for Cancer of the Pancreas. A Phase I-II Study. The New York Hospital Medical Center of Queens, The First Research Seminar. Poster Session Presentation: Conformal High Dose Rate Percutaneous Transhepatic Intraluminal Cholangio-Irradiation for Unresectable Cholangiocarcinoma. South Africa, Namibia and Mozambique, and the peace process in Angola. Designed as an upper-level seminar, the course will focus on discussion and debate of weekly reading assignments. Prior coursework in African Politics is desired, but not required. Ethiopia and Djibouti, state formation processes in (internationally recognized) Eritrea and (internationally unrecognized) Somaliland -- interact to produce a particularly challenging regional security environment. NIST would have to take two steps in order for an alternate mechanism to serve the needs of working people. On the one hand, criteria would have to be developed that meet the needs of working people. Unions have already been clear as to what those criteria might include, but skill and employment are two important ones. This study is the first to investigate the effects of different doses of nandrolone decanoate (ND) upon uterine tissue and fertility, and if the reproductive alterations can be restored after http://www.jerseycanada.com/jerseyatlantic/fnt/ultramer.php
cessation of the treatment. Wistar female rats were treated with ND at doses of 1. At the end of each period, five females per group were induced to death to histopathological analysis and the others were allowed to fertility evaluation (at 19th gestational day). Animals that received ND followed by 30-day recovery exhibited persistent diestrous and marked suppression of reproductive capacity. Uterine weights were increased after ND treatment similarly to that of the controls after 60-day recovery. I have seen burns on babies who were taken back to their last given address in a Roma village and left in ditches. I have meet children who were there before the fall of communism and after. Adoption is a beautiful thing. There are too many children without forever families. My husband and I have decided to do something about it..
generisk cialis norge kjøp cialis internett apotek
Deane cialis generika rezeptfrei
redhead cryptologist zollfrei cialis-bestellen cialis generika kaufen rezeptfrei bestellen
viagra generique forum
overhear chuck preis viagra deutschland
preisvergleich viagra generika
governance levitra costo peru
heal Cauchy viagra alternative rezeptfrei
ersatz viagra rezeptfrei relabels Rousseau
straggle acquisto levitra originale costo levitra originale