

	Things to Know Managing Your Child's PKU Ordering KUVAN


	Patient Support & Assistance Programs FAQ BPPS Program K-PAP Program NORD Assistance


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Patient Support & Assistance Programs

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BioMarin is committed to helping patients and clinicians to navigate the insurance process for access to KUVAN.

BPPS – BioMarin Patient and Physician Support

BPPS is here to work with you, your doctor's office, and your health insurance company. BPPS does the majority of the work and handles most of the details for you! We will research insurance coverage and assist in obtaining access to KUVAN. Most insurance companies cover KUVAN with a reasonable co-payment (the average co-payment is $50 per month, but this varies from plan to plan). BPPS will assist in coordinating other patient services, such as:

Specialty pharmacy– arranging KUVAN to be delivered directly to your home.

K-PAP – KUVAN Patient Assistance Program

Provides KUVAN at no charge for eligible patients without insurance coverage.
Provides alternative coverage by researching insurance options if the patient is uninsured or has inadequate coverage.

NORD – National Organization for Rare Disorders

Provides premium and co-payment assistance for KUVAN, and other assistance with costs directly related to your PKU treatment.

Please direct any questions on these topics to BPPS at 1-877-MY-KUVAN (1-877-695-8826) or e-mail This e-mail address is being protected from spambots. You need JavaScript enabled to view it . For Frequently Asked Questions on all of these topics, click here.

BPPS Program

K-PAP Program

NORD Assistance

Indication

KUVAN^® (sapropterin dihydrochloride) Tablets are approved to reduce blood Phe levels in patients with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin- (BH4-) responsive Phenylketonuria (PKU). KUVAN is to be used in conjunction with a low-Phe diet.

Important Safety Information

High blood Phe levels are toxic to the brain and can lead to lower intelligence and decrease in the ability to focus, remember and organize information. Any change you make to your diet may impact your blood Phe level. Follow your doctor's instructions carefully. Your doctor and dietitian will continue to monitor your diet and blood Phe levels throughout your treatment with KUVAN.

If you have a fever, or if you are sick, your Phe level may go up. Tell your doctor and dietitian as soon as possible so they can see if they have to adjust your treatment to help keep your blood Phe levels in the desired range.

KUVAN is a prescription medicine and should not be taken by people who are allergic to any of its ingredients. Tell your doctor if you have ever had liver or kidney problems, are nursing or pregnant or may become pregnant, have poor nutrition or are anorexic. Your doctor will decide if KUVAN is right for you. Tell your doctor about all the medicines you take.

The most common side effects reported when using KUVAN are headache, diarrhea, abdominal pain, upper respiratory tract infection (like a cold), throat pain, vomiting, and nausea.

To report SUSPECTED ADVERSE REACTIONS, contact BioMarin Pharmaceutical Inc. at 1-866-906-6100, or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please read the full Patient Information by clicking here.

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