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K-PAP—KUVAN Patient Assistance Program

When You Don't Have Insurance Coverage

If you do not have insurance coverage for KUVAN and BPPS cannot find another insurer, BPPS will refer you to the KUVAN Patient Assistance Program (K-PAP). K-PAP provides KUVAN at no charge to qualified patients, on a case-by-case basis, who do not have insurance coverage for KUVAN.

The K-PAP process

You will need to complete an additional application packet and BPPS will work with your doctor to obtain a prescription. Once the application and prescription are received, a shipment of KUVAN will be arranged to be delivered to your home.

Please note that K-PAP is a program of last resort. Therefore, patients who are referred to K-PAP must meet general eligibility requirements and must be willing to work with BPPS to identify and secure alternative sources for prescription coverage.

Timing

If you remain adherent with treatment and work with BPPS to attempt to obtain other kinds of coverage for KUVAN, you are eligible for K-PAP for up to 12 months. You must re-apply annually to K-PAP.

Contacting K-PAP

You can call BPPS case managers who provide K-PAP assistance to patients Monday through Friday from 6 AM to 5 PM (PT) at 1-877-MY-KUVAN (1-877-695-8826).

K-PAP FAQ

BPPS Program

NORD Assistance

Indication

KUVAN^® (sapropterin dihydrochloride) Tablets are approved to reduce blood Phe levels in patients with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin- (BH4-) responsive Phenylketonuria (PKU). KUVAN is to be used in conjunction with a low-Phe diet.

Important Safety Information

High blood Phe levels are toxic to the brain and can lead to lower intelligence and decrease in the ability to focus, remember and organize information. Any change you make to your diet may impact your blood Phe level. Follow your doctor's instructions carefully. Your doctor and dietitian will continue to monitor your diet and blood Phe levels throughout your treatment with KUVAN.

If you have a fever, or if you are sick, your Phe level may go up. Tell your doctor and dietitian as soon as possible so they can see if they have to adjust your treatment to help keep your blood Phe levels in the desired range.

KUVAN is a prescription medicine and should not be taken by people who are allergic to any of its ingredients. Tell your doctor if you have ever had liver or kidney problems, are nursing or pregnant or may become pregnant, have poor nutrition or are anorexic. Your doctor will decide if KUVAN is right for you. Tell your doctor about all the medicines you take.

The most common side effects reported when using KUVAN are headache, diarrhea, abdominal pain, upper respiratory tract infection (like a cold), throat pain, vomiting, and nausea.

To report SUSPECTED ADVERSE REACTIONS, contact BioMarin Pharmaceutical Inc. at 1-866-906-6100, or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please read the full Patient Information by clicking here.

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