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	Managing PKU Low-Phe for Life Diet & KUVAN Control Starts in the Kitchen Eating Low-Phe on the Go Find a Friend for Support PKU & Pregnancy


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Control Starts in the Kitchen

How a low-Phe diet can help you

Research has shown that adults who stay on diet do better in a wide range of areas than those who don't stay on the low-Phe diet. Specifically, adults on a low-Phe diet are more likely than those off diet to:

Graduate with an advanced degree
Belong to a higher socioeconomic class
Have fewer mental problems, such as phobias, panic attacks, and depression
Experience fewer recurrent headaches
Have fewer attention deficiencies
Think faster

Control starts in the kitchen

As a teen starting to make more of your own decisions, it's a good idea to learn how to cook for yourself. That way, when you get older, you'll already have some cooking experience.

As an adult, finding time to make homemade meals can be difficult, especially if your workdays are long. So, you might want to devote one day of the week to cook all of your meals for the entire week. A little up-front work makes the rest of the week's meals quick and easy.

Divide—and conquer

Conquer the urge to splurge by having your low-Phe food within easy reach:

Divide the freshly prepared food into appropriate portion sizes
Store individual servings in plastic containers
Freeze these portions for quick, microwaveable meals during the week
Don't forget breakfast. Pre-measure your favorite cereal, then store it in plastic sandwich bags for quick breakfasts throughout the week

Looking for a good PKU-friendly recipe? Visit PKU.com and cookforlove.org for great low-Phe recipes that will prove that managing PKU can still be delicious.

Eating on the Go

Indication

KUVAN^® (sapropterin dihydrochloride) Tablets are approved to reduce blood Phe levels in patients with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin- (BH4-) responsive Phenylketonuria (PKU). KUVAN is to be used in conjunction with a low-Phe diet.

Important Safety Information

High blood Phe levels are toxic to the brain and can lead to lower intelligence and decrease in the ability to focus, remember and organize information. Any change you make to your diet may impact your blood Phe level. Follow your doctor's instructions carefully. Your doctor and dietitian will continue to monitor your diet and blood Phe levels throughout your treatment with KUVAN.

If you have a fever, or if you are sick, your Phe level may go up. Tell your doctor and dietitian as soon as possible so they can see if they have to adjust your treatment to help keep your blood Phe levels in the desired range.

KUVAN is a prescription medicine and should not be taken by people who are allergic to any of its ingredients. Tell your doctor if you have ever had liver or kidney problems, are nursing or pregnant or may become pregnant, have poor nutrition or are anorexic. Your doctor will decide if KUVAN is right for you. Tell your doctor about all the medicines you take.

The most common side effects reported when using KUVAN are headache, diarrhea, abdominal pain, upper respiratory tract infection (like a cold), throat pain, vomiting, and nausea.

To report SUSPECTED ADVERSE REACTIONS, contact BioMarin Pharmaceutical Inc. at 1-866-906-6100, or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please read the full Patient Information by clicking here.

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