KUVAN is not available at your neighborhood pharmacy. Instead, it is conveniently dispensed by a specialty pharmacy. BPPS will arrange for the specialty pharmacy to ship KUVAN to your home. Most shipments take 2 to 3 days to arrive, but in emergency cases, specialty pharmacies can ship KUVAN via next-day delivery.

The specialty pharmacy process

Once BPPS has completed the insurance authorization process for you, BPPS will notify you that the case has been referred to a specialty pharmacy for dispensing. The specialty pharmacy will call you to confirm your insurance coverage and the co-payment amount, and arrange for KUVAN delivery. The specialty pharmacy will also call 7–10 days before the next refill date to schedule future product shipments. Therefore, be sure to return any phone calls from the specialty pharmacy promptly.

Contacting the specialty pharmacy

Contact BPPS by telephone at 1-877-MY-KUVAN (1-877-695-8826) with any questions about the specialty pharmacy. The phone number of the specific specialty pharmacy assigned to you will be provided by your BPPS case manager.

More information about specialty pharmacies

If you have more questions about specialty pharmacies, please click here to see our Frequently Asked Questions About Specialty Pharmacies section.

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Indication

KUVAN^® (sapropterin dihydrochloride) Tablets is approved to reduce blood Phe levels in patients with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin- (BH4-) responsive Phenylketonuria (PKU). KUVAN is to be used in conjunction with a Phe-restricted diet.

Important Safety Information

High blood Phe levels are toxic to the brain and can lead to lower intelligence and decrease in the ability to focus, remember and organize information. Any change you make to your diet may impact your blood Phe level. Follow your doctor’s instructions carefully. Your doctor and dietitian will continue to monitor and may adjust your diet throughout your treatment with KUVAN.

If you have a fever, or if you are sick, your Phe level may go up. Tell your doctor and dietitian as soon as possible so they can see if they have to adjust your treatment to help keep your blood Phe levels in the desired range.

KUVAN is a prescription medicine and should not be taken by people who are allergic to any of its ingredients. Tell your doctor if you have ever had liver or kidney problems, are nursing or pregnant or may become pregnant, have poor nutrition or are anorexic. Your doctor will decide if KUVAN is right for you. Tell your doctor about all the medicines you take.

The most common side effects reported when using KUVAN are headache, diarrhea, abdominal pain, upper respiratory tract infection (like a cold), throat pain, vomiting, and nausea.

To report SUSPECTED ADVERSE REACTIONS, contact BioMarin Pharmaceutical Inc. at 1-866-906-6100, or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please read the full Patient Information by clicking here.