If BPPS discovers that you do not have insurance coverage for KUVAN and is not successful in locating insurance coverage for KUVAN, BPPS will refer you to K-PAP. K-PAP provides KUVAN at no charge to qualified patients, on a case-by-case basis, who do not have insurance coverage for KUVAN.

The K-PAP process

BPPS will already have the forms you and your doctor and/or dietitian completed, but you will need to complete an additional application packet.
K-PAP will work with your doctor to obtain a prescription for the initial 30-day shipment. Once the application and prescription are received, the K-PAP specialty pharmacy will contact you to arrange for product shipment. If you respond to treatment, K-PAP will work with you and your doctor to obtain a follow-up prescription.

Please note that K-PAP is a program of last resort. Therefore, patients who are referred to K-PAP must meet general eligibility requirements and must be willing to work with BPPS to identify and secure alternative sources for prescription coverage.

Timing

If you remain compliant with treatment and work with BPPS to attempt to obtain other kinds of coverage for KUVAN, you are eligible for K-PAP for up to 12 months. You must reapply annually to K-PAP.

Contacting K-PAP

You can call BPPS case managers who provide K-PAP assistance to patients Monday through Friday from 7 AM to 4 PM (PT) at 1-877-MY-KUVAN (1-877-695-8826). The BPPS case managers can mail the K-PAP application packet to you to get you started on this program.

More information about K-PAP

If you have more questions about K-PAP, please click here to see our Frequently Asked Questions About K-PAP section.

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Indication

KUVAN^® (sapropterin dihydrochloride) Tablets is approved to reduce blood Phe levels in patients with hyperphenylalaninemia (HPA) due to tetrahydrobiopterin- (BH4-) responsive Phenylketonuria (PKU). KUVAN is to be used with a Phe-restricted diet.

Important Safety Information

High blood Phe levels are toxic to the brain and can lead to lower intelligence and decrease in the ability to focus, remember and organize information. Any change you make to your diet may impact your blood Phe level. Follow your doctor’s instructions carefully. Your doctor and dietitian will continue to monitor and may adjust your diet throughout your treatment with KUVAN.

If you have a fever, or if you are sick, your Phe level may go up. Tell your doctor and dietitian as soon as possible so they can see if they have to adjust your treatment to help keep your blood Phe levels in the desired range.

KUVAN is a prescription medicine and should not be taken by people who are allergic to any of its ingredients. Tell your doctor if you have ever had liver or kidney problems, are nursing or pregnant or may become pregnant, have poor nutrition or are anorexic. Your doctor will decide if KUVAN is right for you. Tell your doctor about all the medicines you take.

The most common side effects reported when using KUVAN are headache, diarrhea, abdominal pain, upper respiratory tract infection (like a cold), throat pain, vomiting, and nausea.

To report SUSPECTED ADVERSE REACTIONS, contact BioMarin Pharmaceutical Inc. at 1-866-906-6100, or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please read the full Patient Information by clicking here.